GNAS Antibody | CSB-PA352389LA01HU

GNAS Antibody | CSB-PA352389LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: GNAS

Aliases: Guanine nucleotide-binding protein G (s) subunit alpha isoforms short (Adenylate cyclase-stimulating G alpha protein), GNAS, GNAS1 GSP

Background: Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs) (PubMed:17110384) . Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP (PubMed:26206488, PubMed:8702665) . GNAS functions downstream of several GPCRs, including beta-adrenergic receptors (PubMed:21488135) . Stimulates the Ras signaling pathway via RAPGEF2 (PubMed:12391161) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P63092

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Recombinant Human Guanine nucleotide-binding protein G (s) subunit alpha isoforms short protein (1-394AA)

Immunogen Species: Human

Applications: ELISA, WB, IHC, IF

Tested Applications: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:5000

Dilution Ratio3: IHC:1:20-1:200

Dilution Ratio4: IF:1:50-1:200

Dilution Ratio5:

Dilution Ratio6:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Cancer;Metabolism;Signal transduction