gag Antibody, FITC conjugated | CSB-PA356017DC01MHK

gag Antibody, FITC conjugated | CSB-PA356017DC01MHK | Cusabio

gag Antibody, FITC conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: gag

Aliases: Gag polyprotein (Pr65gag) (Core polyprotein) [Cleaved into: Matrix protein p15 (MA) ; RNA-binding phosphoprotein p12 (pp12) ; Capsid protein p30 (CA) ; Nucleocapsid protein p10-Gag (NC-gag) ], gag

Background: Gag polyprotein plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugate ubiquitin molecules to Gag, or to Gag binding host factors. Interaction with HECT ubiquitin ligases probably link the viral protein to the host ESCRT pathway and facilitate release.Matrix protein p15 targets Gag and gag-pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex.Capsid protein p30 forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.Nucleocapsid protein p10 is involved in the packaging and encapsidation of two copies of the genome. Binds with high affinity to conserved UCUG elements within the packaging signal, located near the 5'-end of the genome. This binding is dependent on genome dimerization.

Isotype: IgG

Conjugate: FITC

Clonality: Polyclonal

Uniport ID: P03332

Host Species: Rabbit

Species Reactivity: Moloney murine leukemia virus

Immunogen: Recombinant Moloney murine leukemia virus Gag polyprotein protein (216-478AA)

Immunogen Species: Moloney murine leukemia virus

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Others

Research Areas: Others