GAD2 Antibody | CSB-PA997765

GAD2 Antibody | CSB-PA997765 | Cusabio

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Product Type: Polyclonal Antibody

Target Names: GAD2

Aliases: glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)

Background: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q05329

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Synthetic peptide of human GAD2

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC;ELISA:1:1000-1:5000, IHC:1:25-1:100

Purification Method: Antigen affinity purification

Dilution Ratio1: ELISA:1:1000-1:5000

Dilution Ratio2: IHC:1:25-1:100

Dilution Ratio3:

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Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Neuroscience