FAT4 Antibody | CSB-PA017577

FAT4 Antibody | CSB-PA017577 | Cusabio

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Product Type: Polyclonal Antibody

Target Names: FAT4

Aliases: FAT tumor suppressor homolog 4 (Drosophila)

Background: FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP) . FAT4 undergo the first proteolytic cleavage by Furin and are predicted to undergo the second cleavage by γ secretase to release intracellular domain (ICD) . FAT4 directly interacts with MPDZ/MUPP1 to recruit membrane associated guanylate kinase MPP5/PALS1. FAT4 is involved in the maintenance of PCP and inhibition of cell proliferation.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q6V0I7

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Synthetic peptide of human FAT4

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100

Purification Method: Antigen affinity purification

Dilution Ratio1: ELISA:1:2000-1:5000

Dilution Ratio2: IHC:1:25-1:100

Dilution Ratio3:

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Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Cancer;Signal transduction