Cusabio Polyclonal Antibodies
FADD Antibody | CSB-PA824751
- SKU:
- CSB-PA824751
- Availability:
- 3 to 7 Working Days
Description
FADD Antibody | CSB-PA824751 | Cusabio
FADD Antibody is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Polyclonal Antibody
Target Names: FADD
Aliases: Fas (TNFRSF6) -associated via death domain
Background: The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: Q13158
Host Species: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Fusion protein of human FADD
Immunogen Species: Human
Applications: ELISA, WB, IHC
Tested Applications: ELISA, WB, IHC;ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:100
Purification Method: Antigen affinity purification
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:1000-1:5000
Dilution Ratio3: IHC:1:50-1:100
Dilution Ratio4:
Dilution Ratio5:
Dilution Ratio6:
Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Cell Biology
Research Areas: Cancer;Cell biology