F Antibody | CSB-PA356041LA01HTO

F Antibody | CSB-PA356041LA01HTO | Cusabio

F Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: F

Aliases: Fusion glycoprotein F0 (Protein F) [Cleaved into: Fusion glycoprotein F2'; Interchain peptide; Fusion glycoprotein F2; Fusion glycoprotein F1], F

Background: During virus entry, induces fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. The fusogenic activity is inactive untill entry into host cell endosome, where a furin-like protease cleaves off a small peptide between F1 and F2 (PubMed:18216092) . Interacts directly with heparan sulfate and may participates in virus attachment (PubMed:10864656) . Furthermore, the F2 subunit was identifed as the major determinant of RSV host cell specificity (PubMed:11493675) . Later in infection, proteins F expressed at the plasma membrane of infected cells can mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis. The fusion protein is also able to trigger p53-dependent apoptosis (PubMed:12663767) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P03420

Host Species: Rabbit

Species Reactivity: Human respiRatory syncytial virus A

Immunogen: Recombinant Human respiratory syncytial virus A Fusion glycoprotein F0 protein (27-529AA)

Immunogen Species: Human respiratory syncytial virus A

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Others

Research Areas: Others