Cusabio Polyclonal Antibodies
EYA2 Antibody, HRP conjugated | CSB-PA007907LB01HU
- 3 to 7 Working Days
EYA2 Antibody, HRP conjugated | CSB-PA007907LB01HU | Cusabio
EYA2 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: EYA2
Aliases: Eyes absent homolog 2 (EC 18.104.22.168), EYA2, EAB1
Background: Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1.
Uniport ID: O00167
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Eyes absent homolog 2 protein (1-514AA)
Immunogen Species: Human
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Epigenetics & Nuclear Signaling;Neuroscience;Signal transduction