Cusabio Polyclonal Antibodies
EPHA1 Antibody | CSB-PA007720LA01HU
- SKU:
- CSB-PA007720LA01HU
- Availability:
- 3 to 7 Working Days
Description
EPHA1 Antibody | CSB-PA007720LA01HU | Cusabio
EPHA1 Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: EPHA1
Aliases: Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH), EPHA1, EPH EPHT EPHT1
Background: Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: P21709
Host Species: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Recombinant Human Ephrin type-A receptor 1 protein (296-414AA)
Immunogen Species: Human
Applications: ELISA, WB, IHC, IF
Tested Applications: ELISA, WB, IHC, IF; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200
Purification Method: >95%, Protein G purified
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:1000-1:5000
Dilution Ratio3: IHC:1:20-1:200
Dilution Ratio4: IF:1:50-1:200
Dilution Ratio5:
Dilution Ratio6:
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Cardiovascular
Research Areas: Neuroscience;Cardiovascular;Signal transduction