EHD3 Antibody, Biotin conjugated | CSB-PA878940LD01HU

EHD3 Antibody, Biotin conjugated | CSB-PA878940LD01HU | Cusabio

EHD3 Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: EHD3

Aliases: EH domain-containing protein 3 (PAST homolog 3), EHD3, EHD2 PAST3

Background: ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (PubMed:25686250) . In vitro causes tubulation of endocytic membranes (PubMed:24019528) . Binding to phosphatidic acid induces its membrane tubulation activity (By similarity) . Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology (PubMed:16251358, PubMed:17233914, PubMed:19139087, PubMed:23781025) . Involved in the recycling of internalized D1 dopamine receptor (PubMed:21791287) . Plays a role in cardiac protein trafficking probably implicating ANK2 (PubMed:20489164) . Involved in the ventricular membrane targeting of SLC8A1 and CACNA1C and probably the atrial membrane localization of CACNA1GG and CACNA1H implicated in the regulation of atrial myocyte exitability and cardiac conduction (By similarity) . In conjunction with EHD4 may be involved in endocytic trafficking of KDR/VEGFR2 implicated in control of glomerular function (By similarity) . Involved in the rapid recycling of integrin beta-3 implicated in cell adhesion maintenance (PubMed:23781025) . Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing (By similarity) . Plays a role in the formation of the ciliary vesicle, an early step in cilium biogenesis; possibly sharing redundant functions with EHD1 (PubMed:25686250) .

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: Q9NZN3

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human EH domain-containing protein 3 protein (269-498AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Others

Research Areas: Others