EDEM2 Antibody | CSB-PA861146LA01HU

EDEM2 Antibody | CSB-PA861146LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: EDEM2

Aliases: ER degradation-enhancing alpha-mannosidase-like protein 2, EDEM2, C20orf31 C20orf49

Background: Initiates the endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2 (PubMed:25092655) . Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q9BV94

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human ER degradation-enhancing alpha-mannosidase-like protein 2 protein (22-300AA)

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IHC:1:20-1:200

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction