DNAJB6 Antibody, Biotin conjugated | CSB-PA03239D0Rb

DNAJB6 Antibody, Biotin conjugated | CSB-PA03239D0Rb | Cusabio

DNAJB6 Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: DNAJB6

Aliases: DnaJ homolog subfamily B member 6 (HHDJ1) (Heat shock protein J2) (HSJ-2) (MRJ) (MSJ-1), DNAJB6, HSJ2 MRJ MSJ1

Background: Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity.

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: O75190

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human DnaJ homolog subfamily B member 6 protein (208-326AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Neuroscience;Signal transduction