DMRT1 Antibody, FITC conjugated | CSB-PA896914LC01HU

DMRT1 Antibody, FITC conjugated | CSB-PA896914LC01HU | Cusabio

DMRT1 Antibody, FITC conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: DMRT1

Aliases: Doublesex- and mab-3-related transcription factor 1 (DM domain expressed in testis protein 1), DMRT1, DMT1

Background: Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA) -dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1. Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminization: represses transcription of female promoting genes such as FOXL2 and activates male-specific genes. May act as a tumor suppressor. May also play a minor role in oogenesis (By similarity) .

Isotype: IgG

Conjugate: FITC

Clonality: Polyclonal

Uniport ID: Q9Y5R6

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Doublesex- and mab-3-related transcription factor 1 protein (195-363AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling