DMGDH Antibody | CSB-PA699345

DMGDH Antibody | CSB-PA699345 | Cusabio

DMGDH Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: DMGDH

Aliases: dimethylglycine dehydrogenase; mitochondrial; EC 1.5.99.2; M2GD; ME2GLYDH

Background: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.

Binzak B.A., Mol. Genet. Metab. 69:181-187 (2000) .
Binzak B.A., Am. J. Hum. Genet. 68:839-847 (2001) .
Moolenaar S.H., Clin. Chem. 45:459-464 (1999)

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q9UI17

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Synthesized peptide derived from C-terminal of human DMGDH.

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:3000

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:3000

Dilution Ratio3:

Dilution Ratio4:

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Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Neuroscience;Metabolism;Signal transduction