Dio3 Antibody | CSB-PA344617LA01RA

Dio3 Antibody | CSB-PA344617LA01RA | Cusabio

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Product Type: Polyclonal Antibody

Target Names: Dio3

Aliases: Thyroxine 5-deiodinase (EC 1.21.99.3) (5DIII) (DIOIII) (Type 3 DI) (Type III iodothyronine deiodinase), Dio3, Itdi3 Txdi3

Background: Responsible for the deiodination of T4 (3, 5, 3', 5'-tetraiodothyronine) into RT3 (3, 3', 5'-triiodothyronine) and of T3 (3, 5, 3'-triiodothyronine) into T2 (3, 3'-diiodothyronine) . RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P49897

Host Species: Rabbit

Species Reactivity: Rat

Immunogen: Recombinant Rat Thyroxine 5-deiodinase protein (37-278AA)

Immunogen Species: Rat

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Neuroscience;Cancer;Metabolism;Signal transduction