DDIT4L Antibody | CSB-PA049554

DDIT4L Antibody | CSB-PA049554 | Cusabio

DDIT4L Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: DDIT4L

Aliases: DNA-damage-inducible transcript 4-like

Background: REDD-2 (regulated in development and DNA damage response 2), also designated Rtp801L or DDIT4L (DNA-damage-inducible transcript 4-like), is a 193 amino acid cytoplasmic protein belonging to the DDIT4 family and is predominantly expressed in skeletal muscle. Considered a stress-inducted protein, REDD-2 is a negative regulator of the mTOR (mammalian target of rapamycin) pathway. mTOR is a serine/threonine kinase that plays an essential role in cell growth control and is an important regulator of skeletal muscle size. Highly expressed in human atherosclerotic lesions and macrophages, REDD-2 mediates monocyte cell death through reduction of Trx (thioredoxin-1) expression. REDD2 expression in macrophages increases oxidized LDL (oxLDL) -induced cell death, suggesting that REDD2 may play a critical role in arterial pathology.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q96D03

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Fusion protein of human DDIT4L

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100

Purification Method: Antigen affinity purification

Dilution Ratio1: ELISA:1:1000-1:2000

Dilution Ratio2: IHC:1:25-1:100

Dilution Ratio3:

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Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Cell biology