CYBB Antibody | CSB-PA006325KA01HU

CYBB Antibody | CSB-PA006325KA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: CYBB

Aliases: CYBB; CGD; GP91-1; GP91-PHOX; GP91PHOX; NOX2; p91-PHOX

Background: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD) . In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cells respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P04839

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Recombinant protein of human CYBB

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

Purification Method: Affinity purification

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:2000

Dilution Ratio3: IHC:1:50-1:200

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Immunology

Research Areas: Cancer;Immunology;Metabolism