Cusabio Monoclonal Antibodies
CST3 Monoclonal Antibody | CSB-MA061901A0m
- SKU:
- CSB-MA061901A0m
- Availability:
- 3 to 7 Working Days
Description
CST3 Monoclonal Antibody | CSB-MA061901A0m | Cusabio
CST3 Monoclonal Antibody is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Monoclonal Antibody
Target Name: CST3
Aliases: CysC, Cystatin-3, Gamma-trace, Neuroendocrine basic polypeptide, Post-gamma-globulin
Relevance: Defects in CST3 are the cause of amyloidosis type 6 (AMYL6) [MIM:105150]; also known as hereditary cerebral hemorrhage with amyloidosis (HCHWA) , cerebral amyloid angiopathy (CAA) or cerebroarterial amyloidosis Icelandic type. AMYL6 is a hereditary generalized amyloidosis due to cystatin C amyloid deposition. Cystatin C amyloid accumulates in the walls of arteries, arterioles, and sometimes capillaries and veins of the brain, and in various organs including lymphoid tissue, spleen, salivary glands, and seminal vesicles. Amyloid deposition in the cerebral vessels results in cerebral amyloid angiopathy, cerebral hemorrhage and premature stroke. Cystatin C levels in the cerebrospinal fluid are abnormally low.Genetic variations in CST3 are associated with age-related macular degeneration type 11 (ARMD11) [MIM:611953]. ARMD is a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane.
Isotype: IgG2b
Conjugate: Non-conjugated
Clone Number: 3A1B7
Uniport ID: P01034
Alternatives To SCBT: sc-51857/sc-66100/sc-73878
Host Species: Mouse
Species Reactivity: Human
Immunogen: Recombinant Human Cystatin C protein
Immunogen Species: Human
Applications: ELISA, IHC
Tested Applications: ELISA, IHC;Recommended dilution:IHC:1:50-1:500
Purification Method: >95%, Protein G purified
Dilution Ratio1: IHC:1:50-1:500
Dilution Ratio2:
Dilution Ratio3:
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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Tags & Cell Markers
Research Areas: Cardiovascular;Cell biology;Tags & Cell Markers;Stem cells