Cusabio Polyclonal Antibodies
CSPG4 Antibody | CSB-PA006076ESR1HU
- SKU:
- CSB-PA006076ESR1HU
- Availability:
- 3 to 7 Working Days
Description
CSPG4 Antibody | CSB-PA006076ESR1HU | Cusabio
CSPG4 Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: CSPG4
Aliases: Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan), CSPG4, MCSP
Background: Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2 (VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: Q6UVK1
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Chondroitin sulfate proteoglycan 4 protein (1950-2210AA)
Immunogen Species: Human
Applications: ELISA, WB, IHC
Tested Applications: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200
Purification Method: Antigen Affinity Purified
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:1000-1:5000
Dilution Ratio3: IHC:1:20-1:200
Dilution Ratio4:
Dilution Ratio5:
Dilution Ratio6:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Neuroscience
Research Areas: Neuroscience;Cancer;Tags & Cell Markers