CPNE1 Antibody | CSB-PA859524LA01HU

CPNE1 Antibody | CSB-PA859524LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: CPNE1

Aliases: Copine-1 (Chromobindin 17) (Copine I), CPNE1, CPN1

Background: Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes (PubMed:14674885) . Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner (PubMed:14674885) . Exhibits calcium-dependent phospholipid binding properties (PubMed:9430674, PubMed:19539605) . Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner (PubMed:23263657, PubMed:25450385) . May recruit target proteins to the cell membrane in a calcium-dependent manner (PubMed:12522145) . May function in membrane trafficking (PubMed:9430674) . Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit (PubMed:18212740) . Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL (PubMed:18212740) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q99829

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Copine-1 protein (326-537AA)

Immunogen Species: Homo sapiens (Human)

Applications: ELISA, IHC

Tested Applications: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Purification Method: Antigen Affinity Purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IHC:1:20-1:200

Dilution Ratio3:

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Dilution Ratio6:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction