Cusabio Polyclonal Antibodies
Cobra venom factor Antibody | CSB-PA856221LA01NAF
- SKU:
- CSB-PA856221LA01NAF
- Availability:
- 3 to 7 Working Days
Description
Cobra venom factor Antibody | CSB-PA856221LA01NAF | Cusabio
Cobra venom factor Antibody is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Polyclonal Antibody
Target Names:
Aliases: Cobra venom factor (CVF) (CVFk) (Complement C3 homolog) [Cleaved into: Cobra venom factor alpha chain; Cobra venom factor gamma chain; Cobra venom factor beta chain]
Background: Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI) . Therefore, CVF continuously activates complement resulting in the depletion of complement activity.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: Q91132
Host Species: Rabbit
Species Reactivity: Naja kaouthia
Immunogen: Recombinant Naja kaouthia Cobra venom factor protein (733-984AA)
Immunogen Species: Naja kaouthia
Applications: ELISA, WB
Tested Applications: ELISA, WB; Recommended dilution: WB:1:500-1:5000
Purification Method: >95%, Protein G purified
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:5000
Dilution Ratio3:
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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Others
Research Areas: Others