CLIC4 Antibody | CSB-PA091447

CLIC4 Antibody | CSB-PA091447 | Cusabio

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Product Type: Polyclonal Antibody

Target Names: CLIC4

Aliases: chloride intracellular channel 4 (mitochondrial) ; D0Jmb3; mc3s5; mtCLIC; TU-74

Background: Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis) .

Wiemann S., Genome Res. 11:422-435 (2001) .
Edwards J.C.; Am. J. Physiol. 276:F398-F408 (1999) .
Chuang J.Z., J. Neurosci. 19:2919-2928 (1999) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q9Y696

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Synthesized peptide derived from N-terminal of human CLIC4.

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:3000

Dilution Ratio3: IHC:1:50-1:100

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Epigenetics & Nuclear Signaling;Cancer;Cell biology;Metabolism;Signal transduction