Cusabio Polyclonal Antibodies
CHMP1B Antibody | CSB-PA748726ESR2HU
- SKU:
- CSB-PA748726ESR2HU
- Availability:
- 3 to 7 Working Days
Description
CHMP1B Antibody | CSB-PA748726ESR2HU | Cusabio
CHMP1B Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: CHMP1B
Aliases: Charged multivesicular body protein 1b (CHMP1.5) (Chromatin-modifying protein 1b) (CHMP1b) (Vacuolar protein sorting-associated protein 46-2) (Vps46-2) (hVps46-2), CHMP1B, C18orf2
Background: Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I, -II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses) . ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B and SPAST to the midbody of dividing cells. Involved in HIV-1 p6- and p9-dependent virus release.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: Q7LBR1
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Charged multivesicular body protein 1b protein (1-199AA)
Immunogen Species: Human
Applications: ELISA, IHC
Tested Applications: ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Purification Method: Antigen Affinity Purified
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: IHC:1:20-1:200
Dilution Ratio3:
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Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Others
Research Areas: Others