CHGA Monoclonal Antibody | CSB-MA0053441A0m

CHGA Monoclonal Antibody | CSB-MA0053441A0m | Cusabio

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Product Type: Monoclonal Antibody

Target Name: CHGA

Aliases: Chromogranin-A, CgA, Pituitary secretory protein I, SP-I, Vasostatin II, CHGA

Relevance: Chromogranin A is a member of the granin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine) . CgA is one of the most used tumor markers in NET's (neuroendocrine tumors) , and elevated CgA concentrations have been demonstrated in serum or plasma of patients with different types of these tumors. However, CgA is not a tumor-specific antigen for NETs, and an abnormal concentration has been described in some non-malignant diseases such as renal failure, heart failure, proton pump inhibition, gastritis, hypertension, or patients with liver diseases.

Isotype: IgG1

Conjugate: Non-conjugated

Clone Number: 1A11C11

Uniport ID: P10645

Alternatives To SCBT: sc-47714/sc-53013/sc-271738/sc-376813/sc-376827

Host Species: Mouse

Species Reactivity: Human

Immunogen: Recombinant CHGA Protein

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC;Recommended dilution:WB:1:500-1:5000, IHC:1:50-1:500

Purification Method: >95%, Protein G purified

Dilution Ratio1: WB:1:500-1:5000

Dilution Ratio2: IHC:1:50-1:500

Dilution Ratio3:

Dilution Ratio4:

Dilution Ratio5:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Neuroscience;Cancer;Tags & Cell Markers;Signal transduction