CHEK1 Antibody | CSB-PA927149

CHEK1 Antibody | CSB-PA927149 | Cusabio

CHEK1 Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: CHEK1

Aliases: checkpoint kinase 1

Background: The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: O14757

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Synthetic peptide of human CHEK1

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;ELISA:1:1000-1:2000, WB:1:200-1:1000

Purification Method: Antigen affinity purification

Dilution Ratio1: ELISA:1:1000-1:2000

Dilution Ratio2: WB:1:200-1:1000

Dilution Ratio3:

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling;Cancer