CDC42 Antibody | CSB-RA177985A0HU
- 3 to 7 Working Days
CDC42 Antibody | CSB-RA177985A0HU | Cusabio
CDC42 Antibody is Available at Gentaur Genprice with the fastest delivery.
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Antibody Type: Recombinant
Target Names: CDC42
Aliases: Cell division control protein 42 homolog (G25K GTP-binding protein), CDC42
Background: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration. Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal neurons. Facilitates filopodia formation upon DOCK11-activation (By similarity).
Isotype: Rabbit IgG
Clone Number: 3C3
Uniport ID: P60953
Modified: Epigenetics and Nuclear Signaling; Cancer; Cell biology; Signal transduction
species: Homo sapiens (Human)
Species Reactivity: Human, Mouse
Immunogen: A synthesized peptide derived from human CDC42
Tested Applications: ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200
Purification Method: Affinity-chromatography
Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.