CD46 Antibody, HRP conjugated | CSB-PA004939EB01HU

CD46 Antibody, HRP conjugated | CSB-PA004939EB01HU | Cusabio

CD46 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: CD46

Aliases: Membrane cofactor protein (TLX) (Trophoblast leukocyte common antigen) (CD antigen CD46), CD46, MCP MIC10

Background: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: P15529

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Membrane cofactor protein (164-325AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Immunology

Research Areas: Immunology