Cusabio Monoclonal Antibodies
CD44 Monoclonal Antibody | CSB-MA004938A0m
- SKU:
- CSB-MA004938A0m
- Availability:
- 3 to 7 Working Days
Description
CD44 Monoclonal Antibody | CSB-MA004938A0m | Cusabio
CD44 Monoclonal Antibody is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Monoclonal Antibody
Target Name: CD44
Aliases: CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I, CD44, CD44, LHR, MDU2, MDU3, MIC4
Relevance: Receptor for hyaluronic acid (HA) . Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs) . Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity) .
Isotype: IgG1, Igk
Conjugate: Non-conjugated
Clone Number: 6G2D2
Uniport ID: P16070
Alternatives To SCBT: #N/A
Host Species: Mouse
Species Reactivity: Human
Immunogen: Recombinant Human CD44 antigen protein (21-220AA)
Immunogen Species: Human
Applications: ELISA, WB, IHC, IF, FC
Tested Applications: ELISA, WB, IHC, IF, FC; Recommended dilution: WB:1:1000-1:40000, IHC:1:50-1:200, IF:1:50-1:200
Purification Method: >95%, Protein G purified
Dilution Ratio1: WB:1:1000-1:40000
Dilution Ratio2: IHC:1:50-1:200
Dilution Ratio3: IF:1:50-1:200
Dilution Ratio4:
Dilution Ratio5:
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Immunology
Research Areas: Immunology