CCL2 Monoclonal Antibody | CSB-MA058641A0m

CCL2 Monoclonal Antibody | CSB-MA058641A0m | Cusabio

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Product Type: Monoclonal Antibody

Target Name: CCL2

Aliases: Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, Small-inducible cytokine A2, CCL2, MCP1, SCYA2

Relevance: Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. [1] "Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF) ."Furutani Y., Nomura H., Notake M., Oyamada Y., Fukui T., Yamada M., Larsen C.G., Oppenheim J.J., Matsushima K.Biochem. Biophys. Res. Commun. 159:249-255 (1989) [2] "The human homolog of the JE gene encodes a monocyte secretory protein."Rollins B.J., Stier P., Ernst T., Wong G.G.Mol. Cell. Biol. 9:4687-4695 (1989) [3] "Human monocyte chemoattractant protein-1 (MCP-1) . Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE."Yoshimura T., Yuhki N., Moore S.K., Appella E., Lerman M.I., Leonard E.J.FEBS Lett. 244:487-493 (1989)

Isotype: IgG2b

Conjugate: Non-conjugated

Clone Number: 3D2E5

Uniport ID: P13500

Alternatives To SCBT: sc-52877/sc-377082/sc-130328/sc-32781/sc-32771/sc-32819/sc-32786

Host Species: Mouse

Species Reactivity: Human

Immunogen: Recombinant Human C-C motif chemokine 2

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC;Recommended dilution:IHC:1:50-1:500

Purification Method: >95%, Protein G purified

Dilution Ratio1: IHC:1:50-1:500

Dilution Ratio2:

Dilution Ratio3:

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Dilution Ratio5:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Immunology

Research Areas: Cancer;Cardiovascular;Immunology;Metabolism