Cusabio Recombinant Antibodies
CASP3 Antibody | CSB-RA286668A0HU
- 3 to 7 Working Days
CASP3 Antibody | CSB-RA286668A0HU | Cusabio
CASP3 Antibody is Available at Gentaur Genprice with the fastest delivery.
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Antibody Type: Recombinant
Target Names: CASP3
Aliases: Caspase-3 (CASP-3) (EC 188.8.131.52) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17, Caspase-3 subunit p12], CASP3, CPP32
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Isotype: Rabbit IgG
Clone Number: 5B2
Uniport ID: P42574
Modified: Cancer; Cell biology; Metabolism
species: Homo sapiens (Human)
Species Reactivity: Human
Immunogen: A synthesized peptide derived from human pro Caspase 3
Tested Applications: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200
Purification Method: Affinity-chromatography
Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.