BRAP Antibody, HRP conjugated | CSB-PA773793LB01HU

BRAP Antibody, HRP conjugated | CSB-PA773793LB01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: BRAP

Aliases: BRCA1-associated protein (EC 2.3.2.27) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (RING-type E3 ubiquitin transferase BRAP2) (Renal carcinoma antigen NY-REN-63), BRAP, RNF52

Background: Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: Q7Z569

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human BRCA1-associated protein (13-124AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling;Signal transduction