Cusabio Polyclonal Antibodies
BRAP Antibody, Biotin conjugated | CSB-PA773793LD01HU
- 3 to 7 Working Days
BRAP Antibody, Biotin conjugated | CSB-PA773793LD01HU | Cusabio
BRAP Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: BRAP
Aliases: BRCA1-associated protein (EC 188.8.131.52) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (RING-type E3 ubiquitin transferase BRAP2) (Renal carcinoma antigen NY-REN-63), BRAP, RNF52
Background: Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
Uniport ID: Q7Z569
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human BRCA1-associated protein (13-124AA)
Immunogen Species: Human
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Epigenetics and Nuclear Signaling
Research Areas: Epigenetics & Nuclear Signaling;Signal transduction