BCL2L1 (Ab-62) Antibody | CSB-PA923588

BCL2L1 (Ab-62) Antibody | CSB-PA923588 | Cusabio

BCL2L1 (Ab-62) Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: BCL2L1

Aliases: Apoptosis regulator Bcl-X

Background: Potent inhibitor of cell death. Isoform Bcl-X (L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases By similarity. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X (S) isoform promotes apoptosis.

Basu A, et.al. (2003) Mar 13; 538 (1-3) : 41-7
Cheng E.H.-Y. et.al. (1996) Nature 379:554-556.
Sattler M. et.al. (1997), Science 275:983-986.
Muchmore S.W.et.al (1996) .Nature 381:335-341
Yu J., Zhang L. Mol. (2001) Cell 7:673-682

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q07817

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Peptide sequence around aa.60~64 (A-D-S-P-A) derived from human BCL-XL .

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:1000

Purification Method: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:1000

Dilution Ratio3:

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Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Cancer;Cell biology;Metabolism;Signal transduction