BCL2 (Ab-56) Antibody | CSB-PA187601

BCL2 (Ab-56) Antibody | CSB-PA187601 | Cusabio

BCL2 (Ab-56) Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: BCL2

Aliases: BCL2

Background: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) .

Ling, Y. H. et al. (1998) J. Biol. Chem. 273, 18984-18991.
Huang, S.J. and Cidlowski, J.A. (2002) FASEB 16, 825-832.
Deng, X. et al. (2001) J. Biol. Chem. 276, 23681-23688.
Huang ST, et al. (2002) FASEB J Jun; 16 (8) : 825-32.
Yamamoto, K. et al. (1999) Mol. Cell. Biol. 19, 8469-8478.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P10415

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Peptide sequence around aa. 54~58 (G-H-T-P-H) derived from Human BCL-2.

Immunogen Species: Human

Applications: ELISA, WB, IHC, IF

Tested Applications: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

Purification Method: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:1000

Dilution Ratio3: IHC:1:50-1:200

Dilution Ratio4: IF:1:100-1:200

Dilution Ratio5:

Dilution Ratio6:

Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Cancer;Cell biology;Metabolism;Signal transduction