BAX (Ab-167) Antibody | CSB-PA834415

BAX (Ab-167) Antibody | CSB-PA834415 | Cusabio

BAX (Ab-167) Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: BAX

Aliases: Apoptosis regulator BAX; membrane isoform alpha; BAXA; Bcl2-associated X protein;

Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

Oltvai Z.N., Cell 74:609-619 (1993) .
Cuddeback S.M., J. Biol. Chem. 276:20559-20565 (2001) .
Guo B., Nature 423:456-461 (2003)

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q07812

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Synthesized non-phosphopeptide derived from human Bax around the phosphorylation site of threonine 167 (F-G-T (p) -P-T) .

Immunogen Species: Human

Applications: ELISA, WB, IF

Tested Applications: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:3000

Dilution Ratio3: IF:1:100-1:500

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Cancer;Cell biology;Metabolism