Cusabio Polyclonal Antibodies
AURKC Antibody | CSB-PA002460LA01HU
- SKU:
- CSB-PA002460LA01HU
- Availability:
- 3 to 7 Working Days
Description
AURKC Antibody | CSB-PA002460LA01HU | Cusabio
AURKC Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: AURKC
Aliases: Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C), AURKC, AIE2 AIK3 AIRK3 ARK3 STK13
Background: Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. AURKC phosphorylates the CPC complex subunits BIRC5/survivin and INCENP leading to increased AURKC activity. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: Q9UQB9
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Aurora kinase C protein (12-143AA)
Immunogen Species: Human
Applications: ELISA, WB, IHC, IF
Tested Applications: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200
Purification Method: >95%, Protein G purified
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:5000
Dilution Ratio3: IHC:1:20-1:200
Dilution Ratio4: IF:1:50-1:200
Dilution Ratio5:
Dilution Ratio6:
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Cell Biology
Research Areas: Cell biology