ATG8 Antibody, FITC conjugated | CSB-PA739788HC01CZI

ATG8 Antibody, FITC conjugated | CSB-PA739788HC01CZI | Cusabio

ATG8 Antibody, FITC conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: ATG8

Aliases: Autophagy-related protein 8 (Autophagy-related ubiquitin-like modifier ATG8), ATG8, AUT7

Background: Ubiquitin-like modifier involved in cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes formation. With ATG4, mediates the delivery of the vesicles and autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.

Isotype: IgG

Conjugate: FITC

Clonality: Polyclonal

Uniport ID: Q6FXR8

Host Species: Rabbit

Species Reactivity: Candida glabrata

Immunogen: Recombinant Candida glabrata Autophagy-related protein 8 protein (1-116AA)

Immunogen Species: Candida glabrata

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Others

Research Areas: Others