ATG14 Antibody, HRP conjugated | CSB-PA741052LB01HU

ATG14 Antibody, HRP conjugated | CSB-PA741052LB01HU | Cusabio

ATG14 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: ATG14

Aliases: Beclin 1-associated autophagy-related key regulator (Barkor) (Autophagy-related protein 14-like protein) (Atg14L), ATG14, ATG14L KIAA0831

Background: Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (PubMed:18843052, PubMed:19050071) . Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine (PubMed:19270696, PubMed:20713597) . Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (PubMed:20713597) . Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (PubMed:23878393) . Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK (PubMed:23878393) . Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion (PubMed:25686604) . Modulates the hepatic lipid metabolism (By similarity) .

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: Q6ZNE5

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Beclin 1-associated autophagy-related key regulator protein (1-492AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction