ATG1 Antibody | CSB-PA738902LA01CZI

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€315.80 - €488.70
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ATG1 Antibody | CSB-PA738902LA01CZI | Cusabio

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Product Type: Polyclonal Antibody

Target Names: ATG1

Aliases: Serine/threonine-protein kinase ATG1 (EC (Autophagy-related protein 1), ATG1

Background: Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates. Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q6FL58

Host Species: Rabbit

Species Reactivity: Candida glabrata

Immunogen: Recombinant Candida glabrata Serine/threonine-protein kinase ATG1 protein (11-312AA)

Immunogen Species: Candida glabrata

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Others

Research Areas: Others

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