ASPN Antibody | CSB-PA002230LA01HU

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SKU:
CSB-PA002230LA01HU
Availability:
3 to 7 Working Days
  • ASPN Antibody
  • Western blot<br />
 All lanes: ASPN antibody at 14 µg/ml<br />
 Lane 1: Mouse heart tissue<br />
 Lane 2: Mouse liver tissue<br />
 Lane 3: HL60 whole cell lysate<br />
 Secondary<br />
 Goat polyclonal to rabbit IgG at 1/10000 dilution<br />
 Predicted band size: 43 kDa<br />
 Observed band size: 43 kDa<br />
  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA002230LA01HU at dilution of 1:100
  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA002230LA01HU at dilution of 1:100
€315.80 - €488.70

Description

ASPN Antibody | CSB-PA002230LA01HU | Cusabio

ASPN Antibody is Available at Gentaur Genprice with the fastest delivery.

Online Order Payment is possible or send quotation to info@gentaur.com.

Product Type: Polyclonal Antibody

Target Names: ASPN

Aliases: Asporin (Periodontal ligament-associated protein 1) (PLAP-1), ASPN, PLAP1 SLRR1C

Background: Negatively regulates periodontal ligament (PDL) differentiation and mineralization to ensure that the PDL is not ossified and to maintain homeostasis of the tooth-supporting system. Inhibits BMP2-induced cytodifferentiation of PDL cells by preventing its binding to BMPR1B/BMP type-1B receptor, resulting in inhibition of BMP-dependent activation of SMAD proteins (By similarity) . Critical regulator of TGF-beta in articular cartilage and plays an essential role in cartilage homeostasis and osteoarthritis (OA) pathogenesis. Negatively regulates chondrogenesis in the articular cartilage by blocking the TGF-beta/receptor interaction on the cell surface and inhibiting the canonical TGF-beta/Smad signal. Binds calcium and plays a role in osteoblast-driven collagen biomineralization activity.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q9BXN1

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Recombinant Human Asporin protein (33-380AA)

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:1000-1:5000

Dilution Ratio3: IHC:1:20-1:200

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction

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