ARNT Antibody | CSB-PA174700

ARNT Antibody | CSB-PA174700 | Cusabio

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Product Type: Polyclonal Antibody

Target Names: ARNT

Aliases: Aryl hydrocarbon receptor nuclear translocator; Dioxin receptor; nuclear translocator; HIF-1 beta; Hypoxia-inducible factor 1 beta

Background: Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.

Hoffman E.C., Science 252:954-958 (1991) .
Wang G.L., Proc. Natl. Acad. Sci. U.S.A. 92:5510-5514 (1995) .
Nguyen T.A., Arch. Biochem. Biophys. 367:250-257 (1999) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P27540

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Synthesized peptide derived from internal of human ARNT.

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:3000

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:3000

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Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cardiovascular

Research Areas: Epigenetics & Nuclear Signaling;Cancer;Cardiovascular;Metabolism