ARHGEF7 Antibody | CSB-PA01445A0Rb

ARHGEF7 Antibody | CSB-PA01445A0Rb | Cusabio

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Product Type: Polyclonal Antibody

Target Names: ARHGEF7

Aliases: Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85), ARHGEF7, COOL1 KIAA0142 P85SPR PAK3BP PIXB

Background: Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions By similarity. May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q14155

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Rho guanine nucleotide exchange factor 7 protein (1-250AA)

Immunogen Species: Human

Applications: ELISA, IF, IP

Tested Applications: ELISA, IF, IP; Recommended dilution: IF:1:200-1:500, IP:1:200-1:2000

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IF:1:200-1:500

Dilution Ratio3: IP:1:200-1:2000

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Cancer;Signal transduction