APP Monoclonal Antibody | CSB-MA0019501A0m

APP Monoclonal Antibody | CSB-MA0019501A0m | Cusabio

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Product Type: Monoclonal Antibody

Target Name: APP

Aliases: Amyloid Beta (A4) Precursor Protein, ABPP, APP, Beta-Amyloid Peptide

Relevance: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy) . Multiple transcript variants encoding several different isoforms have been found for this gene.

Isotype:

Conjugate: Non-conjugated

Clone Number: 5A11E5

Uniport ID: P05067

Alternatives To SCBT: sc-53822/sc-32277/sc-58508/sc-28365/sc-65642

Host Species: Mouse

Species Reactivity: Human, Mouse

Immunogen: Recombinant Human APP Protein

Immunogen Species: Human

Applications: ELISA, WB, IHC, IF

Tested Applications: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:500, IF:1:50-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: WB:1:500-1:5000

Dilution Ratio2: IHC:1:50-1:500

Dilution Ratio3: IF:1:50-1:200

Dilution Ratio4:

Dilution Ratio5:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Neuroscience