APOB Antibody | CSB-PA780260
- 3 to 7 Working Days
APOB Antibody | CSB-PA780260 | Cusabio
APOB Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: APOB
Aliases: apolipoprotein B (including Ag (x) antigen)
Background: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.
Uniport ID: P04114
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide of human APOB
Immunogen Species: Human
Applications: ELISA, IHC
Tested Applications: ELISA, IHC;ELISA:1:1000-1:5000, IHC:1:15-1:50
Purification Method: Antigen affinity purification
Dilution Ratio1: ELISA:1:1000-1:5000
Dilution Ratio2: IHC:1:15-1:50
Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Cardiovascular
Research Areas: Cancer;Cardiovascular;Metabolism;Signal transduction