ALOX15B Antibody, Biotin conjugated | CSB-PA001622LD01HU

ALOX15B Antibody, Biotin conjugated | CSB-PA001622LD01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: ALOX15B

Aliases: Arachidonate 15-lipoxygenase B (15-LOX-B) (EC 1.13.11.33) (15-lipoxygenase 2) (15-LOX-2) (Arachidonate 15-lipoxygenase type II) (Linoleate 13-lipoxygenase 15-LOb) (EC 1.13.11.-), ALOX15B

Background: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/ (15S) -HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S) -HPETE to produce (8S, 15S) -diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells.

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: O15296

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Arachidonate 15-lipoxygenase B protein (1-676AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Cancer;Cardiovascular;Metabolism;Signal transduction