Cusabio Recombinant Antibodies
AGO3 Antibody | CSB-RA875700A0HU
- 3 to 7 Working Days
AGO3 Antibody | CSB-RA875700A0HU | Cusabio
AGO3 Antibody is Available at Gentaur Genprice with the fastest delivery.
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Antibody Type: Recombinant Antibody
Target Names: AGO3
Aliases: Protein argonaute-3UniRule annotation, Argonaute RISC catalytic component 3, Eukaryotic translation initiation factor 2C 3UniRule annotation, AGO3, EIF2C3
Background: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. Possesses RNA slicer activity but only on select RNAs bearing 5'- and 3'-flanking sequences to the region of guide-target complementarity (PubMed:29040713).
Isotype: Rabbit IgG
Clone Number: 4F7
Uniport ID: Q9H9G7
Modified: Epigenetics and Nuclear Signaling
Species Reactivity: Human
Immunogen: A synthesized peptide derived from human AGO3
Tested Applications: ELISA
Purification Method: Affinity-chromatography
Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.