ACVR2B Antibody | CSB-PA292270
- 3 to 7 Working Days
ACVR2B Antibody | CSB-PA292270 | Cusabio
ACVR2B Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: ACVR2B
Aliases: activin A receptor, type IIB
Background: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.
Uniport ID: Q13705
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Fusion protein of human ACVR2B
Immunogen Species: Human
Applications: ELISA, IHC
Tested Applications: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100
Purification Method: Antigen affinity purification
Dilution Ratio1: ELISA:1:1000-1:2000
Dilution Ratio2: IHC:1:25-1:100
Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Signal transduction;Stem cells