Cusabio Polyclonal Antibodies
ACLY Antibody | CSB-PA056430
- 3 to 7 Working Days
ACLY Antibody | CSB-PA056430 | Cusabio
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Product Type: Polyclonal Antibody
Target Names: ACLY
Aliases: ATP citrate lyase
Background: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440, 000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.
Uniport ID: P53396
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Fusion protein of human ACLY
Immunogen Species: Human
Applications: ELISA, IHC
Tested Applications: ELISA, IHC;ELISA:1:1000-1:5000, IHC:1:50-1:200
Purification Method: Antigen affinity purification
Dilution Ratio1: ELISA:1:1000-1:5000
Dilution Ratio2: IHC:1:50-1:200
Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Cancer;Metabolism;Signal transduction