Cusabio Polyclonal Antibodies
ABCC2 Antibody | CSB-PA223592
- SKU:
- CSB-PA223592
- Availability:
- 3 to 7 Working Days
Description
ABCC2 Antibody | CSB-PA223592 | Cusabio
ABCC2 Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: ABCC2
Aliases: ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: Q92887
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide of human ABCC2
Immunogen Species: Human
Applications: ELISA, IHC
Tested Applications: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:30-1:150
Purification Method: Antigen affinity purification
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: IHC:1:30-1:150
Dilution Ratio3:
Dilution Ratio4:
Dilution Ratio5:
Dilution Ratio6:
Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Cancer;Metabolism;Signal transduction