WNT5A Antibody | CSB-PA026138LA01HU

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SKU:
CSB-PA026138LA01HU
Availability:
3 to 7 Working Days
  • WNT5A Antibody
  • Western Blot<br />
 Positive WB detected in: Mouse heart tissue<br />
 All lanes: WNT5A antibody at 3µg/ml<br />
 Secondary<br />
 Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
 Predicted band size: 43, 41 kDa<br />
 Observed band size: 43 kDa<br />
  • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA026138LA01HU at dilution of 1:100
  • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA026138LA01HU at dilution of 1:100
  • Immunofluorescent analysis of PC-3 cells using CSB-PA026138LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L)
€315.80 - €488.70

Description

WNT5A Antibody | CSB-PA026138LA01HU | Cusabio

WNT5A Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: WNT5A

Aliases: Protein Wnt-5a, WNT5A

Background: Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation. Stimulates cell migration. Decreases proliferation, migration, invasiveness and clonogenicity of carcinoma cells and may act as a tumor suppressor. Mediates motility of melanoma cells. Required during embryogenesis for extension of the primary anterior-posterior axis and for outgrowth of limbs and the genital tubercle. Inhibits type II collagen expression in chondrocytes.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P41221

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Recombinant Human Protein Wnt-5a protein (62-380AA)

Immunogen Species: Human

Applications: ELISA, WB, IHC, IF

Tested Applications: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:5000

Dilution Ratio3: IHC:1:20-1:200

Dilution Ratio4: IF:1:50-1:200

Dilution Ratio5:

Dilution Ratio6:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Neuroscience;Cancer;Signal transduction;Stem cells

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