Cusabio Polyclonal Antibodies
vpx Antibody | CSB-PA323941HA01SHD
- SKU:
- CSB-PA323941HA01SHD
- Availability:
- 3 to 7 Working Days
Description
vpx Antibody | CSB-PA323941HA01SHD | Cusabio
vpx Antibody is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Polyclonal Antibody
Target Names: vpx
Aliases: Protein Vpx (Viral protein X) (X ORF protein), vpx
Background: Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: P19508
Host Species: Rabbit
Species Reactivity: Simian immunodeficiency virus
Immunogen: Recombinant Simian immunodeficiency virus Protein Vpx protein (1-112AA)
Immunogen Species: Simian immunodeficiency virus
Applications: ELISA
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
Dilution Ratio1:
Dilution Ratio2:
Dilution Ratio3:
Dilution Ratio4:
Dilution Ratio5:
Dilution Ratio6:
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Others
Research Areas: Others